Big Decisions Deserve Confidence

CA9 (CAIX) imaging could help make that happen

Big Decisions Deserve Confidence

CA9 (CAIX) imaging could help make that happen

A new path forward for diagnosing kidney masses

Because imaging technology is limited, biopsy or surgery is currently needed in order to know if a kidney mass is cancer or not.

A new, noninvasive way to identify the most common type of kidney cancer (called clear cell renal cell carcinoma or ccRCC) may be able to help.

This tool, called a CA9 (or CAIX) scan, could potentially identify ccRCC:

  • Without the need for surgery or biopsy
  • Sooner
  • With more accuracy

CA9, or carbonic anhydrase 9 (car-bon-ik an-hi-drase 9), is a protein found in up to 95% of all ccRCC tumors.

A kidney that is almost fully shaded in and says "up to 95% of ccRCC tumors"

How does CA9 imaging work?

CA9 imaging is a specific kind of body scan that helps doctors see if a kidney mass is ccRCC or not. Under the supervision of a doctor, this is how CA9 scanning could work:

  • An injection containing an ingredient called a tracer is given to you
  • You will wait a few days for the tracer to circulate in your body
  • While you are waiting, the tracer searches for and binds to a protein called CA9, if present. This protein is found on the surface of nearly all ccRCC cells
  • A CA9 scan is performed
  • If CA9 is there, it “lights up” on the images, suggesting ccRCC may be present
A young male doctor reviewing information on a tablet with an older couple

How CA9 scans could help guide treatment choices

With clearer information from a CA9 scan, you and your care team could potentially:

  • Confirm if your mass is ccRCC or not, without needing surgery or a biopsy
  • Base your treatment plan on an accurate diagnosis, so that you get the appropriate treatment for your situation
  • Make decisions sooner, reducing the uncertainty that comes with treatment for undiagnosed kidney masses
  • Potentially avoid some procedures by knowing more about your kidney mass

CA9 imaging has the potential to help people with ccRCC receive more personalized care.

How CA9 imaging works

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